Global Microbiome Conservancy

Profs Poyet and Groussin founded the GMbC in 2016, an international non-profit initiative to advance microbiome science equitably and ethically.

Synthetic bacterial communities as therapeutics for gastrointestinal disorders

We rationally designed microbiota-based intervention strategies to modulate the diversity, composition and function of perturbed microbiomes.

Evolution of IgA-bacteria interactions

We investigate the association between host lifestyle, microbiome compositions and IgA-bacteria interactions in the human metaorganism.

Anaerobic culturing

We isolate and characterise human associated bacterial strains from stool samples and intestinal biopsies.

High throughput identification of antigens/peptides associated with autoimmune diseases.

We are implementing a Phage immunoprecipitation sequencing technique (PhIP-Seq) and a Yeast surface display platform (Yeast Display).

Multiomics investigations of microbiomes

Origin, evolution and mechanism of cholesterol metabolism by the human gut microbiome

We explore a new approach aiming to modulate the gut microbiome to reduce blood cholesterol, through the microbial degradation of intestinal cholesterol.

Primary Sclerosing Cholangitis and the gut microbiome

We aim to identify biological markers and investigate the contribution of the gut-liver axis to the pathogenesis of PSC.